PTBP formaldehyde resin is used primarily in adhesives. It is useful as an adhesive in the bonding of shoe components and parts of watch straps, handbags, hats and belts. For this purpose it is frequently combined with natural or synthetic rubber.
PTBP formaldehyde resin has been reported to induce chemical depigmentation (lightening of the skin).
Patients allergic to PTBP formaldehyde resin are probably reacting to a liquid glue or adhesive. They could be using this product at work if they make leather goods, boxes, plywood, or insulation or if they work as dentists or dental technician/hygienists. Patients may be exposed at home if their hobbies include woodworking or ceramics. In either case these patients should change the type of adhesive they are using to one to which is free of PTBP formaldehyde resin. If this is impossible, gloves should be worn for protection, although this may not provide adequate protection. Allergic patients may also develop dermatitis at the site of contact with leather products glued with this agent, such as watch straps, shoes, or handbags, so dermatologists should test these suspected products for confirmation. Patient should be instructed to alert their dentist to their allergy, since this agent may be used in dentistry.
Occupational groups at risk are adhesive workers, plywood & box makers, foundry workers, dental personnel, brake-lining workers, textile manufacturers and handlers, insulation makers, leather finishers, automobile industry workers and shoemakers.