What is it? 
Isoeugenol is a fragrance primarily used in perfumery, personal care products, over-the-counter medicines, and foods.

How can I avoid it? 
Skin contact with Isoeugenol is required for it to cause a rash. Discontinuation of exposure to products containing Isoeugenol should result in improvement and/or resolution of your dermatitis. By law, all products made in the US for topical use have the ingredients listed either on the product package or the box that contains it, so check the labeling of your skin care products for this ingredient. If there is no information, ask your pharmacist or call the company directly. At work, request a material safety data sheet (MSDS) to help identify potential sources of exposure.

Direct contact with foods or products containing Isoeugenol may cause symptoms including burning, irritation and redness. Direct contact may occur on the skin, lips or mouth. It is possible, but rare, that ingestion of this substance could cause generalized symptoms such as itching or redness of the skin.

The avoidance of fragrances and flavoring agents such as Isoeugenol can be difficult, since so many everyday products contain these substances. One should use only fragrance-free cosmetic and household products. “Unscented” products may contain low levels of a fragrance to cover up an undesirable odor and also should be avoided. Products labeled as “hypoallergenic” do not assure that the product is truly free of fragrance.

Since fragrances are complex mixtures of many ingredients, an individual may tolerate one fragrance but not another. A trial-and-error method of avoiding a fragrance allergen in a product can be performed by applying the product to the forearm in the same small area twice a day for a week. If no dermatitis develops, the product may likely be used safely.

Since some fragrances are also flavors, foods can, rarely, cause flare-ups of dermatitis in fragrance-sensitive individuals. Particularly if you have oral or lip allergies as discussed with your health care provider, you should avoid foods prepared with Isoeugenol.

Uses: 
  • Flowers (roses, carnations, hyacinths, and violets)
  • Foods, candies, gums, beverages, various, as a flavoring or spice
    • Allspice
    • Cinnamon
    • Food spices
  • Household products
    • Air Fresheners / Aromatherapy / Potpourri 
    • Cleaning Products / Soaps / (A preferred household cleaner is dilute white vinegar.)
    • Furniture polish 
    • Laundry care (spot treatment detergent, softeners) 
  • Perfumes / Colognes / After-shaves / Toilet water
  • Medications, topical, prescription and over the counter such as:
    • Anesthetics 
    • Antiseptics
    • Creams, Ointments, Solutions 
    • Foot And Other Powders
    • Nasal Decongestants
    • Herbal remedies, including Traditional Chinese Medications
    • Wound Dressings
  • Skin Care Products / Cosmetics
    • Antiperspirants / Deodorants
    • Hair sprays, gels, tonics and lotions
    • Hair Colorants / “Permanents-Relaxers”
    • Soaps / Cleansers
    • Shampoos / Conditioners
    • Moisturizers
    • Make-ups
    • Nail Polish / Nail Polish Remover
    • Powders / Sprays
    • Sunscreens
    • Shaving lotions
    • Perfumes 
  • Oral and Dental Care Products as a flavoring
    • Cough mixtures
    • Dental Cement
    • Dental Impression agents 
    • Toothache drops 
    • Toothpaste / Mouthwash
    • Throat tablets and lozenges
  • Component of essential oils obtained from spices, including cloves, cinnamon leaves, nutmeg, ylang-ylang oil, and carnation scent.
Other Names for Isoeugenol: 
  • 2-Methoxy-4(1-Propyl) Phenol
  • 2-Methoxy-4-preopenylphenol 
  • 4 Propenyl-2-methoxyphenol 
  • 4-Hydroxy-3-methoxy-1-propenyl benzene
  • 4-Propenylguaiacol
  • Benzylisoeugenol
  • Isoeugenol acetate 
  • Isoeugenol methyl ether 
  • Pheol,2-methoxy-4-(1-propenyl)
Potential cross-reaction/co-reacting substances:
  • Balsam of Peru
  • Eugenol 
  • Other fragrances

How safe is it?

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